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@article{SJLS, author = {Kwabena Nimoh and Felix Robertson and John Taylor and Bright Afranie and Sampson Donkor and Susana Nsiah}, title = { Scientific basis of the combination of Coca-Cola drink and tomato paste in the management of anaemia}, journal = {Scientect Journal of Life Sciences}, volume = {1}, number = {1}, year = {2017}, keywords = {}, abstract = {Anaemia is a global health problem affecting people of all works of life. Anaemia has a lot of adverse effects hence the need for a cost-effective and better treatment strategy. Ethnopharmacological information indicates the use of the combination of Coca-Cola drink and tomato paste to manage anaemia in Ghana. The study investigated the effect of the combination of Coca-Cola drink and tomato paste on haemoglobin levels using animal models. 20 male Wistar rats were grouped as normal, 2,4-DNPH only, Coca-Cola drink only (0.5 ml Coca-Cola drink/100 gm b. wt./day), tomato paste only (20 mg tomato paste/100 gm b. wt./day) and combination of Coca-Cola drink and tomato paste (0.5 ml Coca-Cola drink/100 gm b. wt./day and 20 mg tomato paste/100 gm b. wt./day) with 4 animals in each group. Animals in other groups apart from the normal group were injected with 2,4-DNPH consecutively for 7 days (2 mg/100 gm w.bt/day i.p,). Animals in 2,4-DNPH only group were sacrificed on the 8th day. All animals in the remaining groups were maintained till the 21st day. Body weight was significantly reduced (p˂0.05) in all groups with 2,4-DNPH injection in the first 7 days. From the 8th-21st day, body weight was significantly gained (p˂0.05) in the combination of Coca-Cola drink and tomato paste group. Haemoglobin concentration, red blood cell count and packed cell volume were not significantly reduced in the 2,4-DNPH only group. However, haemoglobin concentration, red blood cell count and packed cell volume were significantly increased (p˂0.05) in the tomato paste only group and in the combination of Coca-Cola drink and tomato paste group. Conclusively, a combination of Coca-Cola drink and tomato paste had a significant increase on the haemoglobin levels indicating some haematinic and anti-anaemic potential.}, pages = {16--20}, url = {http://www.scientect.com/journals/index.php/SJLS/article/view/11} }
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